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Lipid excipient emulsifiers
Lipid excipient solubilizers
Lipid excipients for optimizing
Lipid excipient emulsifiers
Lipid excipient emulsifiers for challenging formulations |
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| Products | Chemical Description | Appierance | HLB | Melting Point (Drop Point) |
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| Emulsifier O/W | |||||
| Apifil® | PEG-8 beeswax | Pallets | 9 | 67.5 | |
| Emulcire™ 61 WL 2659 | Mixture of Cetyl alcohol EP/NF and ethoxylated fatty alcohols (Ceteth-20, Steareth-20) EP/NF |
Pallets | 10 | 48.5 | |
| Gelot™ 64 | Mixture of Glycerol monostearate EP/NF and PEG-75 stearate NF/JPE/EP pending |
Pallets | 10 | 59 | |
| Sedefos™ 75 | Mixture of Triceteareth-4 phosphate (and) ethylene glycol stearates EP/NF/JPE (and) diethylene glycol stearates EP/NF/JPE |
Pallets | 10 | 47.5 | |
| Tefose® 63 | Mixture of PEG-6 stearate NF/JPE (and) ethylene glycol stearates EP/NF/JPE (and) PEG-32 stearate NF/JPE/EP pending |
Waxy solid |
9.5 | 48 | |
| Tefose® 1500 | Mixture of PEG-6 stearate NF/JPE (and) PEG-32 stearate NF/JPE/EP pending |
Waxy solid |
10 | 43 | |
| Emulsifier W/O | |||||
| Plurol® Diisostearique |
Triglycerol diisostearate EP Polyglyceryl-3-diisostearate NF |
Viscous liquid | 4.5 | Liquid | |
Lipid excipient solubilizers
| Lipid excipient solubilizers for improved drug delivery |
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| Products | Functionality | Abridged chemical description | HLB | Market reference |
| Solubilizer | ||||
| Labrasol® | O/W surfactant | Caprylocaproyl macrogol-8 glycerides EP/NF | 12 | ASIA, EU, INDIA, USA*, ROW |
| Labrafil® M 1944 CS | O/W surfactant | Oleoyl macrogol-6 glycerides EP/NF | 9 | ASIA, EU, ROW, USA |
| Labrafil® M 2125 CS | O/W surfactant | Linoleoyl macrogol-6 glycerides EP/NF |
9 | EU, ROW, USA |
| Labrafil® M 2130 CS | O/W surfactant | Lauroyl macrogol-6 glycerides EP/NF (semi-solid) |
9 | EU, ROW*, USA* |
| Capryol™ PGMC | W/O surfactant | Propylene glycol monocaprylate (type I) NF | 6 | EU* |
| Capryol™ 90 | W/O surfactant | Propylene glycol monocaprylate (type II) NF |
5 | ASIA, EU# , USA* |
| Lauroglycol™ FCC | W/O surfactant | Propylene glycol monolaurate | 5 | EU, ROW*, USA* (type I) EP/NF |
| Lauroglycol™ 90 | W/O surfactant | Propylene glycol monolaurate (type II) EP/NF | 3 | ASIA, INDIA* |
| Plurol® Oleique CC 497 | W/O surfactant | Polyglyceryl-3 dioleate NF | 3 | EU*, USA* |
| Labrafac™ PG | Oily vehicle | Propylene glycol dicaprylocaprate EP/NF |
1 | ASIA, EU* |
| Labrafac™ Lipophile WL 1349 | Oily vehicle | Medium chain triglycerides EP/NF/JPE | 1 | ASIA, EU, ROW*, USA* |
| Transcutol® P | Solvent | Highly purified diethylene glycol , monoethyl ether EP/NF | / | ASIA, CANAD, EU, ROW, USA |
Lipid excipients for optimizing
| Lipid excipients for optimizing stability and sensorial properties |
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Products |
Abridged chemical description | Appearance | HLB | Melting point °C (Drop point) | Formulation type | Market reference |
| Consistency agent | ||||||
| Compritol® 888 Pellets |
Glycerol dibehenate EP/NF |
Pellets | 2 | 72.5 | Emulsion Ointment | ASIA*, EU, ROW*, USA |
| Geleol™ mono and diglycerides NF |
Glyceryl monostearate 40-55 (type I) EP/NF |
Pellets | 3 | 57.5 | Emulsion Ointment | ASIA, EU, USA |
| Monosteol™ | Propylene glycol monopalmitostearate EP | Waxy solid | 4 | 36.5 | Emulsion Ointment | ASIA, EU, USA |
| Gelucire® 43/01 | Hard fat EP/NF/JPE | Waxy solid | 1 | 43 | Emulsion Ointment | / |